much the same way and with practically the same results as Dr. Fitchett and myself. He found, as we did, that tutin is extremely toxic, the lethal dose to guinea-pigs and rabbits being a few milligrams per kilogram body-weight, and that it is not readily destroyed—e.g., it withstands treatment with acids, and does not lose its properties on standing. Like ourselves, he failed to produce immunity to its action. A large part of his work was done on the fate of tutin in the tissues, and his most striking assertion is that the tutin can be localized in the brain. From our experiments Fitchett and myself had come to the conclusion that tutin attacks the nerve-centres, but Ford goes further and says he is able to prove its existence in the brain as a “detoxified” body which reduces Fehling's solution after being hydrolyzed with HCl. I have repeated his experiments, following his method so far as I can gather it from his paper, but I have not succeeded in getting a positive result. The same problem had presented itself to me before I saw Ford's paper, and I had already done some of the experiments he describes—e.g., I also found that brain-tissue from a recently killed animal does not diminish the toxic power of tutin (Exp. 226).